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As a generalization, phenobarbitaltype inducers tend to more readily lead to increases in liver weight and cause hepatocellular hypertrophy because of the increase in smooth endoplasmic reticulum

Pondarre et al., 2006

In high concentrations, this may result in cellular toxicity [3-6] and has the potential to be neurotoxic [7]

Video Review: Blood Physiology Block 3, Question 8 Explanation Correct Answer: A

Genes involved in ferroptosis

doi: 10.1073/pnas.0705070104
