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The translation of P-gp is downregulated by estrogen in estrogen receptorpositive (ER-positive) breast cancer cell lines without affecting estrogen receptornegative (ER-negative) breast cancer cell lines or DOX-resistant ER-negative ovarian cancer cell lines (264, 265)

Furthermore, its important role in anti-cancer drug resistance has been observed [115]

These findings highlight how dysregulation in NSCs mitochondrial homeostasis can generate pathophysiological consequences that may significantly contribute to disorders characterized by impaired memory circuits, such as AD (Khacho et al., 2016)

Metabolic clustering of risk factors: evaluation of Triglyceride-glucose index (TyG index) for evaluation of insulin resistance. Diabetology & metabolic syndrome vol

This is critical for tissue repair because damaged tissue frequently suffers from impaired vascular supply, and healing cannot proceed at scale without adequate blood flow

Woiciechowsky C, Schning B, Cobanov J, Lanksch WR, Volk HD, Dcke WD