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Additionally, a recent network meta-analysis of 130 RCTs ( n = 1,122,916) related to PE prophylaxis published in 2022 showed that low-molecular weight heparin (RR: 0.60, 0.420.87), aspirin (RR: 0.79, 0.720.86), vitamin D (RR: 0.65, 0.450.95), calcium (RR: 0.71, 0.620.82), and exercise (RR: 0.68, 0.500.92) are effective in preventing PE [45]

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