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Synthesis and transport of cholesterol derivatives, such as 25- and 27-hydroxycholesterol, are disturbed when cells lack hNPC2, but this protein is not strictly needed to transport fluorescent analogs of 25- and 27-hydroxycholesterol out of the lysosomes in human fibroblasts from NPC disease patients (36, 38, 39)

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In our study, we observed upregulation of MAPT (microtubule associated protein tau) mRNA levels in the cortex of the rmTBI group at 48 h, which was significantly different from the non-impacted sham and ALC + rmTBI groups

Overdosage may cause nausea, and withdrawal bleeding may occur in females

CoolSculpting CoolSculpting is a popular non-invasive fat reduction treatment that uses controlled cooling to freeze and destroy fat cells

Conflict of Interest Statement The authors declare that they have no conflict of interest