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Lycopene scavenges free radicals at cellular level due to its attachment in cell membrane thereby may prevent hypercholesterolemia and hyperglycemia along with allied dysfunctions (Marinova et al., 2005[77]

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Furthermore, intravenous glutathione (12 injections of 1,200 mg) showed no benefit for skin lightening compared to placebo in a Pakistani study (Zubair et al., J Pakistan Assoc Dermatol, 2016) [64]

Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta (TGF-beta)/SMAD signaling pathway
