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225 Administration of the PRMT4 inhibitor TP-064 in a mouse model of atherosclerotic cardiovascular disease can induce a decrease in monocyte tumor necrosis factor- (TNF-) secretion, downregulate the gene expression of the glycogen metabolism-related protein G6pc in the liver, and reduce plasma triglyceride levels, exerting regulatory effects from inflammatory and metabolic pathways

Therefore, alternative lipids to prevent aggregate formation have been investigated

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Mass spectrometry identity confirmation: Verifies the peptides molecular weight matches the expected structure of Melanotan II (C50H69N15O9, MW 1,024.18 g/mol) and confirms the cyclic lactam bridge is intact

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