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For example, mitochondrial metabolic disorder affects the alpha-ketoglutarate level, which in turn regulates the activities of ten-eleven-translocation (TET) and lysine demethylases (KDM), which, finally, affects the level of DNA and histone methylation [182]

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Since Y2H assays readily detect very weak interactions, in vitro pull-down assays were also performed to further examine the interactions with MAX2

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We selected the covariates that are likely associated with cognitive functions or the probability of receiving statins, based on previous research and/or our clinical knowledge
