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Some of the serious side effects of Vitamin B12 include serous allergic reaction, narrowing or blocking of blood vessels, thrombocytosis (a disorder where your body produces too many platelets), low potassium levels in body, pulmonary edema (a condition where there is excess fluid in the lungs) and congestive heart failure

While efficacy matters, the tolerability and adverse effect profile often determines whether a treatment is suitable for long-term use

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The post-supplementation erythrograms for the two cases are shared in Table 1

For people with serious deficiencies or absorption issues, this difference can be life-changing