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Transketolases require thiamine pyrophosphate (TPP), vitamin B1, for proper function

These trials should incorporate standardized protocols and biomarker-driven patient stratification to enhance reproducibility and outcome precision (Mushtaq and Rohit, 2025)

Apparent opportunities and hidden pitfalls: the conflicting results of restoring NRF2-regulated redox metabolism in Friedreichs ataxia pre-clinical models and clinical trials

In approximately 50% of LS cases, EC is diagnosed before CRC in instances where the two malignancies are not synchronous, rendering CRC the second primary cancer in these patients

PubMed, Tiihonen, J., et al

doi: 10.1111/j.1440-1746.2006.04138.x