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Elevated endothelin-1 levels have been reported in LongCOVID patients, both with and without ME/CFS, and together with defective eNOS, may indicate a vasoconstrictorvasodilator imbalance [10]
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The ripe seeds of the milk thistle plant are the medicinally active part

Acknowledgements The authors would like to acknowledge financial support for this work from the deanship of scientific research (DSR), University of Tabuk, Tabuk, Saudi Arabia, under the Grant Number S/1438/0014
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