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Description
Saab, A
Although it could be theoretically possible to enhance the reverse cholesterol effects of LXRs without targeting hepatic lipogenesis with the use of LXR-specific ligands since most of the hepatic responses are due to activation of LXR, this will be a difficult challenge as the ligand binding pocket in both isoforms has been shown to be nearly identical
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8 , e1000376 (2010)
[DOI] [PubMed] [Google Scholar] 86.Chen B., Basak S., Chen P., Zhang C., Perry K., Tian S., Yu C., Dong M., Huang L., Bowen M.E., et al
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