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The increased production of reactive oxygen species (ROS) from inflammatory cells and exposure to oxidants from inhaled sources contribute to the elevated oxidative stress observed in COPD, potentially leading to an exacerbated inflammatory response and the generation of lipid peroxidation products [115]

Such dose may include about 200 to about 1000 milligrams (mg) per day

doi: 10.3390/antiox10111743

These results may be explained by an animal study conducted by Attri et al

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