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Furthermore, FMO3 is regulated by farnesoid X receptor (FXR), a nuclear receptor activated by bile acid ( TMAO levels were significantly associated with body mass index (BMI) in healthy adults with different risk factors (Wang et al., 2016), and studies in humans and mice have shown that plasma TMAO levels increased with ageing (Wang et al., 2014

60 Other causes of peripheral vertigo include 1,12,68 : Herpes zoster oticus (reactivation of the virus that causes chicken pox [a condition known as shingles] with lesions affecting the inner ear) Otitis media (inflammation [usually of infectious origin] of the middle ear) Medication side effects and interactions (see Table 2) Concussion with trauma to peripheral vestibular organs Otosclerosis (hardening of middle ear structures) Causes of Central Vertigo Approximately 20% of vertigo cases are due to central causes of which vestibular migraine is one of the most common

However, the same study showed no significant changes in the levels of p-tau181 in the subjective memory complainer (SMC) group (Neth et al., 2020)

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