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It has been proposed that PQQ can mitigate inflammatory and oxidative liver cell damage by downregulating CUL3, a regulatory protein involved in metabolism, antioxidant response, detoxification, cell proliferation/apoptosis in Kupffer cells, which are hepatic liver macrophages [16,44]
Hasanah NT, Dewi TS
In addition, GFP::CUP-5 and mCherry::CUP-5 show the same colocalization with LMP-1 in lysosomes (Fig
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