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Studies showed CJC-1295 DAC increased mean GH plasma levels by 2-10 fold and IGF-1 levels by 1.5-3 fold sustained over multiple weeks with weekly dosing

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[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Challier J.C., DAthis P., Guerre-Millo M., Nandakumaran M

7 The extent of protein translation suppression induced by Localis-REX-assisted nucleus-targeted HNE release was attenuated in cells overexpressing (non-Halo-tagged) NCBP1(C463A) compared to empty vector or (non-Halo-tagged) NCBP1(wt) overexpressing cells, under otherwise identical conditions

Rabia LA, Desai AA, Jhajj HS, et al