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Abbreviations ROS: Reactive Oxygen Species NAC: N-acetyl-L-cysteine TSPCs: Tendon Stem/Progenitor Cells COL1A1: Collagen Type 1 Alpha 1 TNC: Tenascin C SCX: Scleraxis TNMD: Tenomodulin PI3K: Phosphoinositide 3-kinase ECM: Extracellular Matrix OS: Oxidative Stress ROS: Reactive Oxygen Species CCK-8: Cell Counting Kit-8 H 2 O 2 : Hydrogen Peroxide AMI: Arithmetic Means Intensity PBS: Phosphate-Buffered Saline MFI: Mean Fluorescence Intensity SDS: Sodium Dodecyl Sulfate HRP: Horseradish Peroxidase SD: Standard Deviation DEGs: Differentially expressed genes GO: Gene Ontology BP: Biological Process MF: Molecular Function CC: Cellular Component References Pillai DS, Dhinsa BS, Khan WS

Kurhaluk, 2024

Treatment of diabetic mice with a combination of ketogenic diet and aerobic exercise via modulations of PPARs gene programs

GSH functions in several enzyme systems within the body that assist with the quenching of free radicals and the detoxification of fat-soluble compounds (Table 1) (25)

Inhibitory effects of apigenin on the growth of gastric carcinoma SGC-7901 cells

RNA extraction and library preparation for RNA sequencing Total RNA was isolated from formalin-fixed paraffin-embedded (FFPE) PostNAC surgical specimens ( n = 15) from the same patients whose PreNAC biopsy RNA-sequencing (RNA-seq) data had been analyzed in a previous study [12], enabling direct paired transcriptomic comparisons (Additional File 1)