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N-acetylcysteine (NAC) NAC is known as the supplement form of a hospital antidote: doctors give it intravenously to save the liver from an acetaminophen (Tylenol) overdose.58 It works by restoring glutathione, one of the bodys most important antioxidants.59 Clinical trials have also shown NAC can improve survival in some patients with other types of acute liver failure when given early.60 As a supplement, NAC doesnt affect bile flow the way TUDCA does

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*Correspondence: Kyunglim Lee, [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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