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Although it remains challenging to obtain direct evidence, since most available tools, techniques, and model systems lack the resolution to clearly establish causality, many neurodegenerative diseases are strongly associated with energy failure, which ultimately contributes to neuronal death (discussed in more detail later)

Ishimoto Y, Inagi R, Yoshihara D, Kugita M, Nagao S, Shimizu A, Takeda N, Wake M, Honda K, Zhou J, Nangaku M (2017) Mitochondrial abnormality facilitates cyst formation in autosomal dominant polycystic kidney disease

Role of C-Reactive Protein at Sites of Inflammation and Infection

This is characterized by the accumulation of low-density lipoprotein within the artery walls, leading to the formation of atheroma and distinct plaques consisting of proliferative fibrous tissue and calcifications (109, 110)

In my practice, I approach Long COVID the same way I approach other complex chronic conditions, such as Lyme disease, mold-related illness, autoimmune disorders, and chronic fatigue syndrome (ME/CFS)

Ferrannini E, Buzzigoli G, Bevilacqua S, Boni C, Del Chiaro D, Oleggini M, Brandi L, Maccari F: Interaction of carnitine with insulin-stimulated glucose metabolism in humans