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their metabolic activity modulates the neuro-inflammatory milieu and provides trophic support to neurons (Figure 2) (62, 63)

[DOI] [PMC free article] [PubMed] [Google Scholar] 271.Chowdhury, S

Pediatrics 115 , e290e296 (2005)

Cytosolic GSH crosses the mitochondrial outer membrane (MOM) through rapid porin-mediated exchange (Figure 1) and is then transported into the matrix primarily through inner mitochondria membrane (IMM) proteins of the SLC25 family: the dicarboxylate carrier (DIC) and the 2-oxoglutarate carrier (OGC) [36]

Diabetes-induced up-regulation of uncoupling protein-2 results in increased mitochondrial uncoupling in kidney proximal tubular cells

Shapiro H, Kolodziejczyk AA, Halstuch D, Elinav E