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GSTs were shown to catalyze the conjugation between various xenobiotics with electrophilic centers (Figure 1) and the nucleophilic GSH, thus tagging the xenobiotic for vacuolar sequestration (Martinoia et al., 1993)

doi: 10.26355/eurrev_201804_14749 206 PekalaJPatkowska-SokoaBBodkowskiRJamrozDNowakowskiPLochyskiSet al

However, both peptides distribute systemically and show time-independent efficacy neither requires circadian optimization

Study of changes in serum copper level in patients with acute myocardial infarction

While both amino acid replacements have side chains that are polar as opposed to the original glycine, aspartic acid also introduces a negative charge to the surrounding, as well as being larger than serine