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Description
Western blot analysis HaCaT cells (Anweisci, Shanghai, China) were cultured in petri dishes until the cell density reached 80%, and then the cells were exposed to 100 g/mL TAT-CcSOD1 for varying durations of 0, 15, 30, 60, and 120 min

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10.3945/ajcn.115.120881 147

and downstream effectors, including FOXO, mTORC1, and PPAR, translate these inputs into sustained cytoprotective gene expression

the invention provides methods of preventing or treating muscular weakness in a patient with Parkinson's disease and/or of improving or restoring muscular strength of a patient with Parkinson's disease, by administering one or more hepatocyte growth factor mimics as described herein

These observations implied that integrin-mediated signals normally maintain growth and are blocked by AIIB2
