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Given that protease activity increases at an alkaline pH, the abnormal epidermal barrier function in rosacea might be associated with enhanced activation of epidermal proteases, especially kallikrein (KLK)-5

Moreover, immunofluorescence results showed that Cdc42 and PKCz were colocalized on the cell membrane and the colocalization tended to be on one side rather than the uniform distribution throughout the cell membrane after treatment (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Mayton H.S., Oliver C., Vaughn S.F., Loria R

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