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Figure 12 3.6.4 Metabolic pathway enrichment analysis As shown in Figure 13 , preliminary analysis and found that the main difference pathways between FI group and NC group were Autophagy-other, Autophagy-animal, Glycosylphosphatidyylinositol (GPI)-anchor biosynthesis, Glycerophospholipid metabolism

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Segments of medical-grade silicone tubes were all autoclaved

-GCS produces -glutamyl peptides when the supply of cellular Cys is insufficient, such as in cases of excessive consumption of glutathione for conjugation or under the excessive production of peroxides due to oxidative stress [180]

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Although numerous small molecules evaluated as antioxidants have exhibited therapeutic potential in preclinical studies, clinical trial results have been disappointing