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Effect of combined dasatinib and fisetin treatment on senescent cell clearance in monkeys
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The review documented DSIP's widespread distribution throughout the brain and peripheral tissues, its remarkably stable presence in cerebrospinal fluid, and its unusually long-lasting biological effects despite a short plasma half-life of only minutes

Activation of local inhibitory circuits in the dentate gyrus by adult-born neurons

Mitochondrial oxidative stress is a hallmark of vascular aging and plays a central role in endothelial dysfunction [39,40,41]