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Hair follicles undergo continuous cycles of growth (anagen), regression (catagen), and rest (telogen), with disruptions in this cycle leading to hair loss and thinning

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Individuals frequently exposed to environmental toxins

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Integrins are considered the main cell-adhesion transmembrane receptors that play multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in biochemical and mechanical signals between cells and their environment in a wide range of states in health and diseases