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In studies of myocardial ischemia/reperfusion injury, the cardioprotective effect of SIRT1 was found to be associated with deacetylation of NRF2 [74]

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In mammals, three different insulin/IGF-1 receptor ligands are present: insulin, IGF-1 and IGF-2

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Two data points were omitted from analysis in vehicle group due to extensive food spillage
