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To remove a dark neck permanently, you must address the root cause (like insulin resistance or friction) while using medical treatments like Q-switched Nd:YAG lasers or TCA peels to clear existing pigment
Besides, artemether has also been found to elevate intracellular iron contents of HSCs by obstructing IRP2 ubiquitination degradation, triggering ROS accumulation and ferroptosis (Li et al., 2020)

Association between controlling nutritional status (CONUT) score and body composition, inflammation and frailty in hospitalized elderly patients

[PubMed] [Google Scholar] Roldo M, Barbu E, Brown JF, Laight DW, Smart JD, Tsibouklis J

10.1093/jac/dks138 123 LuoQ.DingN.LiuY.ZhangH.FangY.YinL