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Description
The foregoing findings suggest that endoperoxides such as FINO2 may initiate ferroptosis through multiple mechanisms [13]
MAO, present in the outer mitochondrial membrane, and -ketoglutarate dehydrogenase (-KGDH), the TCA cycle enzyme complex, are able to generate H 2 O 2
Consequently, effectively blocking and reversing these secondary injuries is crucial for inhibiting ferroptosis (Visavadiya et al., 2015)
Glutathione contributes to immune homeostasis , supporting an adequate and well-calibrated response
To denature the proteins, 120 L of 8 M urea in 50 mM Tris-HCl (pH 8) was added
doi: 10.1038/ki.2012.448 125
