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CoQ10 has been investigated for supporting heart function, particularly in individuals with heart failure, though NICE guidance (NG106) does not recommend CoQ10 as standard treatment for heart failure or cardiomyopathies

A 2026 review in the American Journal of Sports Medicine emphasizes that despite popularity, "significant research regarding the safety and efficacy of these therapeutic methods is required before definitive recommendations can be made to patients." Only a single human case series exists for BPC-157 (for knee pain), with significant methodological flaws and no controls

doi: 10.1016/j.biomaterials.2025.123874

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[DOI] [PubMed] [Google Scholar] 72.Hsu C.C., Senussi N.H., Fertrin K.Y., Kowdley K.V

This pathway provides broader brain distribution than the olfactory route alone