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While the exact causes of these erythrocyte changes are due to fibrin amyloid microclots or other factors, such as ROS (which can cause RBC changes as well [367, 368]), remain unclear, they likely contribute to the oxidative stress observed in Long COVID [369, 370]

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Studies show that PFD not only alleviates pulmonary inflammation and collagen deposition but also exerts antifibrotic effects through multiple key signaling pathways

Bioorganic Med Chem Lett (2020) 30(23):127557