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Loebel, C., Rodell, C

Zhao J, et al

These factors may determine abnormal signaling to neural circuits (intrinsic primary afferent nerves and extrinsic primary afferent nerves), which in turn may affect intestinal physiology and sensory perception (197)

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Given the smaller sample sizes available in non-European populations, we did not perform genome-wide association testing in these populations, and instead focused analyses on variants discovered as associated in the European GWAS