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Cacciatore, I., et al., Recent advances in the treatment of neurodegenerative diseases based on GSH delivery systems

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GS deficiency in humans can result in dramatic metabolic consequences because the accumulated -glutamylcysteine is converted to 5-oxoproline, which can cause severe metabolic acidosis, hemolytic anemia and central nervous system damage [137,138]

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And it doesnt just have reduced glutathione, an active form of glutathione that helps with liver health and enzyme activityit also has riboflavin (vitamin B2) to support digestion and energy production, COQ10 for heart and cellular health, and PQQ, another powerful antioxidant

ACSL4 contributes to ferroptosis-mediated rhabdomyolysis in exertional heat stroke