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Description
(PubMed) McCaddon A

A 54-year-old patient with pernicious anemia experienced anaphylactic shock twenty minutes after his sixth hydroxocobalamin shot

Diet, supplements (e.g., niacin, NR), and exercise help, but may not suffice post-40 due to inefficiency and depletion.[18][19] Oral precursors like NMN increase NAD+ but bioavailability varies

High dose oral cobalamin may be a suitable alternative in selective cases, where intramuscular injections are not tolerated and compliance is not a problem

All are available in oral form and sublingual form but not (mainly adenosylcobalmin) all forms are available as a b12 shot

The injection has proven effective in treating B12 deficiency
