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TCDCA activates the FXR-SHP pathway to reduce SREBP-1c, which lowers androgen precursor production (Zheng et al., 2021)

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Drink plenty of fluids, such as water or ORS (Oral Rehydrating Solution), and apply a pain-relieving balm to the head if necessary

Taken together, these results demonstrate that pharmacological Ire1 inhibition suppresses lipid peroxidation induced by renal IRI in vivo, and through this mechanism alleviates renal damages caused by IRI

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