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A study in Canada has shown an incidence of small-duct PSC as 0.15/100 000 [4]

Therefore, a higher level of evidence, such as results from randomized controlled trials, is needed to clarify these findings

According to American Diabetes Association guidelines, treatment should be individualized based on patient tolerance, efficacy, and overall benefit-risk profile

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[DOI] [PubMed] [Google Scholar] 30
