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[DOI] [PubMed] [Google Scholar] 53.Scheenen T.W.J., Klomp D.W.J., Wijnen J.P., Heerschap A

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[413] demonstrated the antifibrotic effects of RES on intestinal smooth muscle cells from a CD rat model, finding that this compound decreased cell numbers through cell cycle arrest and apoptosis, and reduced collagen synthesis and procollagen mRNA expression

The graying process, also known as canities, is caused by the loss of hair color, which also means that the melanocytes are not producing as much melanin as before, therefore they are unable to transfer the melanin to the keratinocytes

Cancer Cell 40 , 439440 (2022)