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Feeding diabetes-prone BioBreeding (BBdp) rats a hydrolyzed casein-based diet, a diet that binds nutritional copper and lowers tissue copper, promotes islet cell neogenesis and results in 23-fold fewer diabetes cases compared with feeding cereal-based diets [ 43 ]

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However, many people struggle to get enough vitamin B12 through diet alone, especially those who follow vegetarian or vegan diets, as plant-based foods generally lack the vitamin

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Response to treatment with GH therapy is variable of 5 patients reported no response was seen in two patients, an equivocal response seen in another two patients and only one patient responded well to therapy (169)