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In the context of STAT pathwaymediated M2 polarization driving an aggressive tumor phenotype, Garcinone E blocks the M2 polarization process by inhibiting STAT6 phosphorylation, while Mongolian Iris Extract specifically targets the IL10/STAT3/PDL1 axis to reverse M2mediated immune evasion [228, 229]
These changes further altered cellular metabolic profiles associated with Parkinsons disease pathophysiology

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Thus, the intracellular growth of MTB can be restricted to BMDCs and eliminated from macrophages

Naturally produced in almost every cell, glutathione plays a leading role in detoxification, antioxidant defence, inflammation regulation (and even graceful aging)

doi: 10.1023/a:1010936227570
