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miR-128 is significantly downregulated in breast and lung cancer tissues 363,364

doi: 10.1038/nrrheum.2012.143 68 HeYHaraHNunezG

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Gene expression studies highlight increased cortical astrocytic activity, coupled with parvalbumin interneuron loss, suggesting a role for astrocytes in neuronal network destabilization 301

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In summary, the VpreB-UR is involved in the interaction with V H and the nature of the V H domain seems to play an important role concerning the magnitude of the effect