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Peroxisomes also contain several oxidases that can generate various ROS, such as superoxide radicals and hydroxyl radicals 5,14

Vitamin C is a water-soluble vitamin (dissolves in water)

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It is genetically inherited and considered an independent risk factor for heart disease

The availability of chemically defined NAPQI enabled these studies to establish that differences in species sensitivity were due to differences in the rate of metabolic conversion of APAP to NAPQI.14 The aforementioned in vitro studies were performed using hepatocytes from a relatively small number of donors ( n = 411)

In contrast, hemolysis was significantly decreased when erythrocytes were pre-treated with Gt28L, MRS, or ascorbic acid