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Lysosomal dysfunction in Down syndrome is APP-dependent and mediated by APP-beta CTF (C99)

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Rossi, M., Piagnerelli, M., Van Meerhaeghe, A

Following primary infection at oral or genital mucosal surfaces, the virion finds its entry into the innervating neuronal axon terminals Fig

Expression of these AR circRNAs was upregulated during castration-resistant progression, with levels of AR circRNAs correlated strongly with those of the linear AR transcripts, indicating a transcriptional mechanism of regulation