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Such dysfunction leads to altered mitochondrial dynamics, impairment of the mitochondrial electron transport chain, increased ROS production, and consequently exacerbates OS [61]

In a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsons disease mouse model, treatment with Lf-ASX-LPs resulted in 5.0-, 3.1-, and 5.6-fold increases in dopamine levels, TH + fiber density, and TH + neurons, respectively, restoring dopaminergic neuron damage