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It is worth noting that cellular senescence also plays important beneficial roles in physiological processes such as tissue development, wound healing, and tumor suppression (Suter et al., 2025)

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Moreover, H 2 O 2 has been shown to induce RIPK1-dependent necroptosis in MEFs 23 , but other studies indicated that RIPK1 and RIPK3 were dispensable 24

Table 1 provides demographics of the participants who underwent each treatment

Maintain a Skincare Routine: Continue to follow a consistent skincare routine that includes gentle cleansing, moisturising, and sunscreen application