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Inhibition of Menin, BCL-2, and FLT3 Combined with a Hypomethylating Agent Cures NPM1/FLT3-ITD/-TKD Mutant AML in a PDX Model

Manning P'22 Andrea J
doi: 10.1007/s00018-020-03656-y 53 BedardKKrauseK-H

V.StathopoulosG

[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Kasprzak J

Acetylcarnitine is highly labeled from glucose in ACLY KO and DKO (Figure 6A), similar to TCA cycle labeling, suggesting that acetylcarnitine reflects and may be in equilibrium with the mitochondrial acetyl-CoA pool
