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It has been suggested [22] that while the biliary excretion of GSH is a passive phenomenon directly related to the intrahepatic concentrations of GSH, the excretion of GSSG into the bile is a carrier-mediated process against a steep concentration gradient
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310 Additional evidence suggests that H 2 S can inhibit the production of inflammatory mediators by immune cells such as T cells and macrophages, highlighting its therapeutic potential in MS treatment 311 (Figs
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