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Sumi T, Harada K

Abstract Cancer cachexia (CC) is characterized by significant skeletal muscle wasting, and contributes to diminished quality of life, while being associated with poorer response to treatment and with reduced survival

Recent experimental therapies, including both in vitro and in vivo studies, have been extensively conducted to investigate the pharmacological properties of natural compounds [37, 38]

Searches using Foldseek 105 suggest that it is a unique structure found only in the DENND4 family members

doi: 10.1111/imm.12774 177

[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Major J.M., Zhou E.H., Wong H.L., Trinidad J.P., Pham T.M., Mehta H., Ding Y., Staffa J.A., Iyasu S., Wang C., Willy M.E