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Subclassing System The most serious imbalance currently facing classes lies in the subclassing system

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Reducing GSH impairs cellular antioxidant regulation, increasing ROS production, thereby accelerating mitochondrial damage and apoptosis induction (101)

As a regulator in bile acid metabolism, FXR not only affects bile acid synthesis, reabsorption, and excretion [104], but also serves as a protector against ferroptosis
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